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Archive for May 2011

Promising TB vaccine candidate progresses to Phase I clinical trials

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JATB is pleased to feature this news from TuBerculosis Vaccine Initiative (TBVI). The news has been released to JATB by TBVI and is carried unedited. The views expressed here are entirely those of TBVI.

The MTBVAC01 vaccine candidate, developed to protect people against tuberculosis, will start Phase I clinical trials early in 2012. This was announced by the Spanish biopharmaceutical company Biofabri. The candidate was developed by the University of Zaragoza, Spain and is part of the international portfolio of TuBerculosis Vaccine Initiative (TBVI). Tuberculosis causes almost two million deaths per year.

During a press conference Biofabri’s CEO Esteban Rodriguez explained that the first batch of the vaccine is now available for toxicity studies. After the results of these studies have been assessed by the European Medicines Agency, responsible for accrediting and authorising, the candidate will move to Phase I of clinical trials in humans. Phase I studies are conducted in small groups of healthy adults to check if the new vaccine can be given without any serious side effects or reaction and that it produces a good immune response. If the results are positive the vaccine candidate will move on to Phase II.

MTBVAC01, designed by TBVI’s research partner Carlos Martin of the University of Zaragoza, could replace the current BCG vaccine. It is the first and leading attenuated live vaccine globally. The results from the laboratory predict a firm protection against TB; this has to be proven in the coming years.

The research team, which has spent four years working on this project, aims to produce a vaccine that will be ‘universally accessible’, protecting millions of people around the world. According to the project’s scientific director Carlos Martin, the disease is becoming more resistant to antibiotics. Tuberculosis is the most important cause of death among people with HIV infection.

Written by JournalistsAgainstTB

May 28, 2011 at 3:11 pm

Posted in TB and Media

Tuberculosis in children: a call to action

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JATB thanks Dr Soumya Swaminathan for this very informative piece on Children and TB.

A severely malnourished young girl, about one and a half years old, was brought to the out-patient department of a busy teaching hospital with symptoms of fever, cough and lethargy for about 10 days. Pneumonia was suspected and confirmed by a chest x-Ray and she was given a course of antibiotics and asked to return for follow-up after a week.

Her frantic mother brought her back to the emergency room after 4 days – by then, she was unconscious and despite all efforts, died the next day. Tests done then showed that she had TB meningitis or TB of the brain in addition to the infection in her lung. This incident, which I witnessed, has always served as a grim reminder to me, that TB in children is not only poorly understood and mis-diagnosed, but often has little room for error and can progress very rapidly in the young child leading to long-term disability or death, as it did in this case.

Worldwide, at least 1 million TB cases occur each year in children under 15 years of age, 75 per cent of these occur in 22 high burden countries. In 2009, India had the highest number of TB cases in the world (approximately 2 million new patients), suggesting that the prevalence in children is also likely to be high. The true burden of TB in children is unknown because of the lack of child-friendly diagnostic tools and inadequate
surveillance and reporting of childhood TB cases. This is a disease where the infection in children is directly related to the prevalence in adults, as it spreads by airborne droplet infection and close contact.

While about half of all Indians have silent or “latent” TB infection, only a small fraction (10 per cent) develop signs and symptoms in their lifetime, in the rest the bacteria seem to live quietly, in harmony with the host. Whether the infection flares up into disease depends on many things, notably the body’s immunity and if that is defective due to HIV or malnutrition or diabetes, then TB gets the upper hand in the battle with the immune system. Age is another important factor and children below 2 or 3 years old not only have a higher risk of developing disease, it is often more severe and widespread.

Pneumonia or infection of the lungs is a leading killer of children, world-wide, accounting for about 20 per cent of deaths in under-five children. Recent studies in Africa showed that TB was a common cause of “pneumonia” in both HIV infected and uninfected children – it was detected only when a special effort was made as part of a research study.

It is likely that more children will be correctly diagnosed if TB is considered as a cause of other common childhood infections. However, it is important to note that the correct tests need to be performed and interpreted properly — another challenge as x-Rays in children are notoriously difficult to read and prone to reader bias.

Perhaps due to the lack of a “gold standard” diagnostic test in children (the sputum test serves as one in adults), a number of unnecessary and useless tests are performed, contributing to a bigger hole in the pocket of the parent, but little else! It has been estimated that in India alone, 15 million dollars are spent annually on serological (ELISA) tests for TB – resources that could be better spent, considering there is no evidence that these tests are useful.

Children with TB infection today represent the reservoir of TB disease tomorrow. If the global goal of eliminating TB by 2050 is to be met, treatment and prevention of TB in children needs as much attention as in adults. Unfortunately, BCG, the only licensed TB vaccine, has limited efficacy against the most common forms of childhood TB and its effect is of limited duration.

There are several clinical trials ongoing to test newer vaccines for TB, but it will take 8-10 years for a more efficacious vaccine to be available for wide use. Most clinical trials for new TB drugs and drug combinations (that will be effective against both drug sensitive and drug resistant TB) are being conducted in adults and do not include children.

While there are obvious ethical as well as practical and logistical issues that need to be addressed while conducting trials in children, excluding them only ensures that they do not benefit from advances in diagnostics, new drugs or preventive strategies. Scientists and researchers need to do a better job of raising awareness, educating and engaging with the community about clinical trials in general and trials in children, in particular, especially since most participants in TB clinical trials tend to be poorly educated and socially disadvantaged.

The National TB Control Program is one of the largest and most successful public health programs in the world, providing high quality services to over 1.4 million patients every year. However, screening of household contacts of adult TB patients and provision of preventive drugs to young childrenmust receive higher priority. As India moves towards universal access to prevention, diagnosis and treatment of TB, the little ones amongst us must not be forgotten.

The author is Coordinator, Research Special Programme for Research and Training in Tropical Diseases, WHO, Geneva

First published in The Hindu – 14 April 2011. Published in JATB with permission from the author.

Written by JournalistsAgainstTB

May 21, 2011 at 3:41 pm

Posted in TB and Media

What can the Global Fund do more of?

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As a part of the Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM) consultation project, the Biennial Partnership Forum 2011, an inclusive online debate was initiated to find answers to some key questions. The answers were expected to contribute towards constructing a more robust roadmap for the future of the Global Fund.

The responses have been wide-ranging – both in suggestions and observations. They reflect the voices, expectations and hopes of affected communities, programme administrators and other stakeholders. They also indicate that GFATM has become a symbol of hope and stakeholders would like to see its scope go beyond just funding country programmes. Regardless of whether or not this is feasible, or fits in with the scope of GFATM, the exercise has succeeded in revealing some very real gaps that need to be addressed. The summary of the responses is available at http://www.citizen-news.org/2011/04/global-fund-consultation-topic-1-lives.html.

It would be valid to begin here by directing some thought towards how the Global Fund is structured and how it is different from other funding agencies. Andreas Tamberg, Fund Portfolio Manager, GFATM says: “The Global Fund is a unique, public-private partnership and international financing institution dedicated to attracting and disbursing additional resources to prevent and treat HIV and AIDS, TB and malaria. This partnership between governments, civil society, the private sector and affected communities represents an innovative approach to international health financing. The Global Fund’s model is based on the concepts of country ownership and performance-based funding, which means that people in countries implement their own programmes based on their priorities and the Global Fund provides financing on the condition that verifiable results are achieved.”

The Country Coordinating Mechanisms (CCMs) established by GFATM to drive country level activities ensure that there is equitable representation from all of the above sectors. Manohar Elavarthi, Vice Chair of the CCM India, corroborates this: “Before the Global Fund was established, we were operating in a traditional world of funding where it was typically bilateral and did not allow space for participation from key stakeholders who would benefit from the funds. The Global Fund in a sense changed much of this. For the first time, we have an agency that allows for this very vital participation through the CCMs. There are other unique elements to the Global Fund as well. It encourages the use of generic drugs, allows for administration by local officials and most importantly optimizes on the resources available by lowering administrative and manpower costs.”

That the Global Fund has touched lives and made a difference is evident from the figures, which speak for themselves (see box at the end of the article). The Global Fund works in close collaboration with other bilateral and multilateral organizations to supplement existing efforts in dealing with the three diseases.

The funding for India is as follows:
Total approved funding as of May 2011
Funding for HIV/AIDS: USD 1,927,801,421
Funding for HIV/TB: USD 14,819,772
Funding for malaria: USD 101,650,559
Funding for TB: USD 352,466,229
(Source for figures: Global Fund)

The need to revisit priorities
Then why is there a need to revisit the funding patterns, or examine whether the Global Fund should increase or decrease what it is currently doing? It is important to view this from different lenses. Within the Global Fund there are questions as to whether systems and processes have become too complex. To quote from the Global Fund’s An Agenda for a More Efficient and Effective Global Fund: “… increased political attention to health, with substantial new resources, has given rise to a proliferation of actors and initiatives and a far more complex global health landscape. The Paris Declaration on Aid Effectiveness and subsequent Accra process have highlighted the need for the Global Fund, along with other donors, to harmonize their efforts and align them more effectively with countries’ own systems and regulations. This need has become particularly acute as AIDS, TB and malaria programs in many countries have rapidly scaled up from demonstration projects to fully fledged national programs. In such a dynamic environment the Global Fund has had to remain a flexible, innovative and learning organization. It has consistently worked to adapt its processes in response to changing circumstances and to effectively use data and operational experience to bring about organizational improvement and increased operational efficiency and effectiveness…”

Viewing it from a stakeholder perspective, the expectations are varied, and some fall in with the above. Dr Mohammed Rafique, Country Team Leader at CARE India, says: “Since the Global Fund bases its funding on local programmes and does not initiate or implement parallel programmes, it is very important to understand local contexts. It is also vital for the Global Fund to recognize that the different political climates of different countries make it impossible for one solution to fit all problems, and thereafter allow for those differences and respond to them accordingly.”

Dr D Behera, Director, LRS Institute of TB and Respiratory Diseases, and CCM Member says: “Global Fund has done a commendable job of providing vital funding for TB programmes in India, but the demand for uptake of funds for TB is rather limited. The reasons for why India continues to grapple with the problem of large incidence of and deaths from TB, lies elsewhere and is not within the purview of the Global Fund. We have to regulate the private sector as this is the first point of contact for patients. When they come into the government programme, most often it is already too late. How can we pull these linkages together?”

Subrat Mohanty, Project Coordinator, Project Axshya, International Union against Tuberculosis and Lung Disease (The Union), adds: “The Global Fund has been supporting the India TB Programme since Round Two through various rounds. It has been a historic moment for TB care and control in India to have two civil society principal recipients – The Union and the World Vision India – along with the Central TB Division to have joined together in the Global Fund Round Nine to support India’s effort to TB care and control. A lot depends on how effectively access to full treatment and awareness on the disease is spread across the country – an area where the usefulness of civil society collaboration and roles for sectors like the media become apparent.”

Linkages – vital to impact
While the above statements might reflect the situation with regard to TB, the situation is true of AIDS and malaria as well. Treatment is vital to saving lives but can the Global Fund help to enable the other linkages? These are important linkages to overall public health, without which real impact is difficult to achieve. Andreas Tamberg says: “At the end of the 1990s, public health experts identified a number of highly effective interventions to prevent and treat AIDS, TB and malaria. New knowledge about the scale of epidemics and a deeper understanding of the complex causal links among poverty, development and disease, pushed international issues of public health to the centre of the world’s development agenda.”

In the coming years, it would be very important for the Global Fund to translate this understanding into action. That linkages in other sectors are also important is evident from the fact that the responses to the online consultation had a significant number of respondents pointing towards the need for more effective measures to prevent diseases. Other demands include collaborative programmes such as training for health workers, health and community systems strengthening and the scaling-up of laboratory services.

The CCM is a vital hub for effective functioning of the Global Fund in each country. Most of the respondents to this story were of the opinion that the purpose would be well served if there was greater representation from non-government entities. “While government representation is very important, it should not result in all the other voices becoming less vocal. It is absolutely imperative for a Global Fund representative to anchor the CCM meetings,” appealed one respondent eloquently.

The India CCM, on the face of it, has very little representation from the TB sector and the emphasis seems more in favour of AIDS. One can rationalise that when AIDS is addressed, TB also gets attention but AIDS and TB can be twinned only to some extent because, while 80 percent of people living with HIV might develop TB at some time, the reverse might not be true. It becomes vital to look at TB as a separate entity and give it special emphasis and this merits greater representation from the TB sector.

In its World Malaria Report 2008, the WHO estimated there had been 10.6 million cases of malaria and 15,000 deaths from the disease in India during 2006.[1] By its very name, the Global Fund concentrates on HIV, TB and malaria. The response to malaria however was seen to be minimal. Mr Nirod Kumar Bhuyan, Project Officer at the LEPRA Society and CCM India member, says: “Malaria is underrepresented in the CCM and the Government of India does not give adequate importance to it despite the fact so many people suffer from malaria in India. Much more needs to be done and the Global Fund has a vital part to play in this.”

Some statistics
* 3 million people currently on antiretroviral treatment for HIV.
* 7.7 million people on effective TB treatment under the internationally approved TB control strategy (DOTS).
* 160 million insecticide-treated bed nets distributed to protect families from malaria.
Additional results in treatment, prevention and care include:
* 150 million people reached with HIV counseling and testing.
* 142.4 million malaria drug treatments delivered.
* 2.7 billion condoms distributed.
* 5 million basic care and support services provided to orphans and vulnerable children.
* 160.4 million people reached with community outreach services.
* 12.3 million people trained to deliver services for prevention and treatment of AIDS, TB or malaria.
(Source for figures: Global Fund)

In conclusion
Global Fund-supported programs have saved so many lives by enabling countries to deliver significantly expanded key services (see figures above ). The emphasis has been on service delivery. Numbers are important but meeting the Millennium Development Goals for HIV, TB and malaria will require huge efforts and commitments in terms of funding, programmes and country specific responses that go beyond the numbers. The consultation has revealed some of the more severe gaps. It remains to be seen how the Global Fund will respond to the challenges.

[1] Source: The Hindu 17 June 2010 http://www.hindu.com/2010/06/17/stories/2010061754161100.htm

Bharathi Ghanashayam

First published in www.healthdev.net

Written by JournalistsAgainstTB

May 16, 2011 at 5:19 pm

Posted in TB and Media

TB is killing women silently

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JATB welcomes Dr Soumya Swaminathan. She is a guest writer we are proud to feature. It is not widely known that tuberculosis is the third major killer of women aged 15-44 years, accounting for approximately 700,000 deaths a year globally. In this very compelling story, she writes about the severe impact that TB has on women. Read on…

As the sun set over the 2,500 year old stupa in Vaishali, Bihar, in the half-light of dusk, a young woman showed me an X-ray that she brought out of a dark and damp corner of her hut. She weighed less than 30kg, looked anaemic and weak and carried a 10 day old infant in her arms, while two other toddlers tugged at her sari. Even in the poor light, I could see that her X-ray had a cavity and white patches in the right lung, a sure sign of tuberculosis, most likely of the infectious variety. She had taken treatment for TB off and on 8 months ago but after several visits to the health centre that did not have a stock of drugs, had given up.

Sputum test
She had been to the local primary health centre recently complaining of cough and fever, had been given cough syrup by the pharmacist and she had also taken several courses of antibiotics from local private practitioners. When she finally had a sputum test done, it was heavily positive for TB bacteria and she was advised a fresh course of TB treatment. Her 10-day old baby girl was underweight and showed no obvious signs of infection but both her other children were found to be infected with TB. I left with a heavy heart, hoping that she had the common or drug-sensitive form of TB where her chances of cure were high if she completed her full course of treatment.

Drug resistant
However, I knew that she had a high chance of having drug resistant TB (because of previous irregular treatment), a form that is notoriously difficult to treat and is associated with a high risk of death. It is not widely known that tuberculosis is the third major killer of women aged 15-44 years, accounting for approximately 700,000 deaths a year globally and causing illness in millions more. TB is more common during and immediately after pregnancy, possibly due to the changes in immunity that occur during that time. This not only poses a risk to the life of the woman but also increases the chances of death in the newborn baby. Babies born to women with TB are also more underweight and are at high risk of developing the disease themselves due to the close contact with their mother. TB can cause infertility and chronic infections of the reproductive system. Malnutrition and food insecurity can exacerbate the risk of TB disease; other threats such as rising tobacco use and diabetes among women, can also mean an increasing burden of TB.

Major impact
The AIDS epidemic has had a major impact on TB rates in many countries, affecting more women and at younger ages than previously. Women living with HIV are 10 times more susceptible to TB than HIV uninfected women. A study in Pune found that TB increased the probability of death for HIV-infected pregnant women and their infants. Further, HIV-positive women with TB during pregnancy had a higher risk of transmitting HIV to their babies compared to women without TB. While nationally, HIV infection in pregnant women is rare, there are 156 districts with higher (greater than 1 per cent) HIV prevalence, where extra attention needs to be paid to screening for both HIV and TB in pregnancy.

There is another, more indirect, but equally serious consequence way of suffering from TB. A study from Chennai estimated that 15 per cent of women who develop TB faced rejection by their families, highlighting the stigma that TB still has in our society today. TB among women also affects children: they are at risk of infection from their main caregivers and are often pulled out of school to help care for sick family members or to provide additional income for the family. TB is associated with and exacerbated by poverty, overcrowding and malnutrition, conditions commonly faced by women, especially in urban slums.

In an attempt to reduce maternal mortality and improve pregnancy outcomes, the government, through the National Rural Health Mission, is making efforts to improve the quality of antenatal care and increase the proportion of institutional deliveries attended by trained personnel.

Screening and treatment of common infectious diseases (TB nationally, HIV and malaria in some regions of India) should be integrated into key entry points to the health system for women, notably antenatal care, family planning services and child immunization visits.

A simple screening tool with four questions (presence of cough, fever, weight loss or absence of weight gain during pregnancy and night sweats) could be used by health workers (ASHAs or Village health nurses) to exclude TB. Those with any of these symptoms need to be further investigated for TB. All pregnant women should be counselled and offered HIV testing and if found to be HIV positive should be further evaluated for antiretroviral treatment, counselled regarding infant feeding and followed-up closely.

Many malaria-endemic countries in Africa use intermittent preventive therapy (IPTp) with anti-malarial drugs during pregnancy to reduce the impact of malaria on mother and child. In the highly malaria endemic regions of India, pregnant women should be counselled to sleep under bednets, screened and treated for malaria if symptomatic and receive preventive therapy if not. In addition to attention to the obstetric causes of maternal mortality, it is time we acted on the less obvious but equally important killers of women.

Dr. SOUMYA SWAMINATHAN is Coordinator, Research at the Special Programme for Research and Training in Tropical Diseases, Geneva

This story was first published in The Hindu 5 May 2010.

Written by JournalistsAgainstTB

May 14, 2011 at 4:59 pm

Posted in TB and Media

What does women’s empowerment really mean?

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On the face of it, this post has nothing to do with TB. And yet, it has deep connections. Let’s look at how many lives of women TB claims across the world. According to a report published by The Lancet, globally, 700 000 women die from tuberculosis every year; this disease kills more women than do all causes of maternal mortality combined. Does this have to do with empowerment or the lack of it? Maybe both.

At a recent blood donation camp held in Bangalore, where I was a participant/volunteer/potential donor, a majority of the women who volunteered to donate blood were found ineligible. These were young women, none more than 28-30 years; they were upwardly mobile young professionals and fitted perfectly into the profile of financially independent, empowered women. And yet, all of them were found to either have low haemoglobin count, low blood pressure, or were underweight. And to stretch an argument, they could at some point of their lives find their health compromised enough to be infected by TB, which lurks around people who provide an environment conducive to its spread. In this scenario, it doesn’t take much to imagine the plight of women who are poor, have to work harder and longer hours at lower wages. They have to also be content with eating leftovers if any, or go hungry. And to top it all, they get least priority for healthcare within their families.

So we come back to empowerment. Have we really understood women’s empowerment? For the woman, does it merely mean salary cheques at the beginning of a month and the freedom to be militant and aggressive? Shouldn’t it also mean the freedom to make informed decisions about what is good for them, negotiate for better health and living conditions, and the right to stand up and be counted?

Women are directly responsible for perpetuating the human race; they nurture families, and above all, they have a duty to keep themselves healthy. Shouldn’t empowerment actually mean the ‘means’ to enable all of this for themselves? Have we somewhere missed the woods for the trees while commuicating messages about women’s empowerment? Are development agencies listening?

Does this connect with TB? It sure does. TB loves people without empowerment, or the wrong kind of empowerment!

Bharathi Ghanashyam

Source for figures on women and TB: http://www.thelancet.com Published online May 19, 2010 DOI:10.1016/S0140-6736(10)60579-X

Written by JournalistsAgainstTB

May 7, 2011 at 5:12 pm

Posted in TB and Media

What makes a good health story?

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What makes a good health story? This is a question that has often confounded me. Writing health stories, fraught as it is with challenges of getting access to the stories themselves, collecting the data, and getting them commissioned, is a daunting task. Added to which is the fact that media space for health stories is shrinking if not non-existent. And yet, health, or the lack of it is an important piece in the jigsaw of human development and needs to be written about.

Writing on health, means telling compelling stories that will engage the reader enough to identify with them and want to act. It means going behind the numbers. For instance, if India has a staggering 2 million deaths owing to TB every year, it is not only the figures, but the human lives behind the figures that become important. Where are these figures coming from? Are they urban or rural people? How do they live? What do they eat? Why are they falling sick? All these have linkages to each other and to larger life issues and without these linkages, we have mere reports and not stories. That makes a huge canvas for a health journalist to fill.

Consider the challenges. First, reporting on health is associated with myriad complexities. The information we put out has to be accurate and simple enough for the lay reader to comprehend. This is not easy because a health story has to include medical terms which are difficult to understand and use in the right context. The subtle difference between incidence and prevalence for example is significant and the terms need to be used correctly. While writing a story on childhood TB, the doctors I spoke to often used the terms pauci-bacillary, AFB etc. I spent anxious moments trying to use them in the right context because I am just a journalist and not a doctor. And remember, journalists are up against deadlines!!

Second, there are two clear parts to a holistic health story. There are the human elements and the hard facts, and journalists need both at the same time regardless of whether they are reporting from the field or from conferences. Journalists are often confounded and befuddled by figures and studies presented through power points at conferences. They then tear their hair apart trying to make enough sense of them to file a readable story. While reporting from the field upwards, they have the human stories but fusing it with the bits that can hold it together is difficult.

Consider the following slides; the first from a conference, the other from the field:

By themselves, neither of these can be used for advocacy. The first dealt only with figures and failed to show the humans behind them. The second merely gave a glimpse into the story of a child’s life. It could at best kindle a bit of sympathy. Neither gave a complete picture. So it is up to a journalist to knit these two elements together. Third, a story makes complete sense only when it reflects the voices of several stakeholders.

Who are the stakeholders to a health story? If the story is about childhood TB for instance, it would obviously first be the child who is affected. But the doctor who is treating the child would be equally important. And this is not enough. The numbers are important because readers want to know how severe the problem is. This is a tough one. Where do we get simple, easy to use numbers? Alongside is the India profile from the WHO website and the data is complex enough to give one sleepless nights!! Interested agencies would be well advised to post special factfiles on their websites, that are relevant for the media and which journalists can decipher and use at short notice. This would serve their cause much better and make our lives simpler!

Further, access to pathologists and radiologists is important because childhood TB diagnosis is a problem. We need experts who can give context and credibility to a story. What the head of a government TB programme says is much more important and credible than what a journalist is saying. That is quite a big wish list. Do we get all of this? Sometimes yes, most often no.

It is absolutely imperative for a journalist to have quick and ready access to experts, professionals, policy makers, activists and grassroots workers. What we need is networks where journalists are equal stakeholders and actively participate in the process of change. We need people to speak with us and not to us. We also need time and effort to be invested in building our knowledge so that we can then write informed, useful articles on health.

I also want to make a distinction here between training and knowledge building. Journalists do not need training on how to write; most of them have reasonably good writing skills and can pull a story together with ease. What they really need is regular interaction with those who know the latest developments, trends, the terminology, and all the other technicalities. I mean the hard stuff about the disease which is so difficult to understand and yet, so vital to write about.

Even if all this is made possible, and there is a good story on hand, I still hosted a party than no one came to, because the truth is that TB does not make news. Speaking of the Indian context, I have it from editors that the urban reader who reads English newspapers does not want to read about TB or other diseases, which are, right or wrong, perceived as diseases of the poor. And therefore these stories are killed. But the good news also is that less than 15 per cent of India’s population reads English newspapers. This means that 85 per cent of the population – a large section of which is ‘poor’ reads vernacular papers and these are still open to us. Currently very little attention is paid to building the capacities of this very vital space. This has to change. And change has to happen fast. There is no time to waste.

Bharathi Ghanashyam

JATB is grateful to the mother of little Sushil (name changed) for letting us use his story in the slide above. Sunil (13), is HIV positive and TB has ravaged his stomach, brain and lungs. Though intensive treatment has helped, there were diagnostic problems. He is presently on ART as well as TB medication. At times, when he is suffering from more than one opportunistic infection (OI), the regimen is intense. His treatment at the charitable SEWA Clinic in Bangalore is supported by Milana, a group that helps families affected by HIV and AIDS.

Written by JournalistsAgainstTB

May 1, 2011 at 11:44 am

Posted in TB and Media